Helicobacter pylori str. 3118

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori str. 3118 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and single-cell arrangement. This organism thrives optimally at a temperature of 37.0°C, aligning with its habitat as a host-associated microbe, likely residing in the gastric mucosa of its host. The microaerophilic nature of H. pylori str. 3118 indicates that it requires reduced levels of oxygen for growth, which is typical for many bacteria inhabiting the gastrointestinal tract where oxygen concentrations are lower than atmospheric levels. This adaptation may play a significant role in its survival and metabolic processes within the acidic environment of the stomach. Understanding the unique traits of Helicobacter pylori str. 3118 contributes to a broader comprehension of its ecological niche and potential interactions within the host. The bacterium's ability to persist in a challenging environment like the stomach underscores its evolutionary adaptations, which may include mechanisms for withstanding acidity and evading host immune responses. Such insights are crucial for exploring its role in gastric health and disease.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strain3118

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. 3118
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 3118 scaffold_9, whole genome shotgun

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

1319 genes

Non-Coding Genes

180 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
dna-binding proteinBB449_01955Not AvailablePositive400960 - 40142117874.9
cysteine desulfurase, nifs familyBB449_01960Not AvailablePositive401594 - 40275742476.1
iron-sulfur cluster assembly scaffold protein nifuBB449_01965Not AvailablePositive402779 - 40375936280.7
copg family transcriptional regulatorBB449_01970Not AvailablePositive403916 - 4041498948.63
hypothetical proteinBB449_05275Not AvailableNegative404904 - 40563227156.7
magnesium and cobalt transport protein coraBB449_05280Not AvailableNegative405639 - 40659537107.6
phosphoglycerate kinaseBB449_05285Not AvailableNegative406611 - 40781944730.3
type i glyceraldehyde-3-phosphate dehydrogenaseBB449_05290Not AvailableNegative407835 - 40882735996.3
uracil-dna glycosylaseBB449_05295Not AvailableNegative408916 - 40961726272.3
acyl-phosphate glycerol 3-phosphate acyltransferaseBB449_05300Not AvailableNegative409614 - 41031526750.8

Displaying genes 381 – 390 of 1499 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total