Helicobacter pylori str. 3118

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori str. 3118 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and single-cell arrangement. This organism thrives optimally at a temperature of 37.0°C, aligning with its habitat as a host-associated microbe, likely residing in the gastric mucosa of its host. The microaerophilic nature of H. pylori str. 3118 indicates that it requires reduced levels of oxygen for growth, which is typical for many bacteria inhabiting the gastrointestinal tract where oxygen concentrations are lower than atmospheric levels. This adaptation may play a significant role in its survival and metabolic processes within the acidic environment of the stomach. Understanding the unique traits of Helicobacter pylori str. 3118 contributes to a broader comprehension of its ecological niche and potential interactions within the host. The bacterium's ability to persist in a challenging environment like the stomach underscores its evolutionary adaptations, which may include mechanisms for withstanding acidity and evading host immune responses. Such insights are crucial for exploring its role in gastric health and disease.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strain3118

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. 3118
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 3118 scaffold_9, whole genome shotgun

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

1319 genes

Non-Coding Genes

180 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
heat-inducible transcription repressorBB449_01445Not AvailableNegative294607 - 29543732021.6
hypothetical proteinBB449_01450Not AvailablePositive295648 - 29628624845.7
hypothetical proteinBB449_01455Not AvailablePositive296307 - 29660311104.5
motility accessory factorBB449_01460Not AvailableNegative296612 - 29849572188.4
flagellin bBB449_01465Not AvailableNegative298556 - 30010053915.3
dna topoisomerase iBB449_01470Not AvailablePositive300266 - 30247683116.2
radical sam proteinBB449_01475Not AvailablePositive302469 - 30339534339.4
hypothetical proteinBB449_01480Not AvailableNegative303543 - 30478147159.3
phosphoenolpyruvate synthaseBB449_01485Not AvailableNegative304878 - 30731691159.3
hypothetical proteinBB449_01490Not AvailablePositive307544 - 3076423491.26

Displaying genes 281 – 290 of 1499 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total