Helicobacter pylori str. 3076

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 3076 is a Gram-negative bacterium characterized by its distinctive spirilla shape and tendency to exist as singles rather than in clusters. This microbe thrives optimally at a temperature of 37.0°C, which corresponds to the internal temperature of the human body, indicating its adaptation to a host-associated habitat. H. pylori strain 3076 is microaerophilic, requiring reduced oxygen levels for optimal growth, which is consistent with its colonization of the gastric mucosa, where oxygen availability is lower than in the atmosphere. The specific adaptations of H. pylori strain 3076 to its microenvironment suggest a highly specialized evolutionary relationship with its host. This strain's capacity to survive and proliferate in the acidic environment of the stomach underscores its potential role in influencing gastric physiology. The microaerophilic nature of this bacterium may also reflect an ecological strategy that minimizes competition with other microbial inhabitants of the gastrointestinal tract, allowing it to occupy a unique niche. Understanding these traits provides insight into the evolutionary pressures that shape the behavior and survival of H. pylori and highlights the intricate dynamics of host-associated microbial communities.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strain3076

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. 3076
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 3076 scaffold_9, whole genome shotgun

Gene Summary

Adenine Count

500194 bp

Thymine Count

506308 bp

Guanine Count

323351 bp

Cytosine Count

318975 bp

Genome Length

1648828 bp

Protein-coding Genes

1455 genes

Non-Coding Genes

64 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
two-component system response regulatorBB451_03925Not AvailablePositive1386558 - 138719924807.1
two-component sensor histidine kinaseBB451_03930Not AvailablePositive1387255 - 138836743036.0
nad(p)h-hydrate epimeraseBB451_03935Not AvailablePositive1388370 - 138976450596.0
replicative dna helicaseBB451_03940Not AvailablePositive1389775 - 139123555488.4
competence proteinBB451_03945Not AvailablePositive1391232 - 139254550465.2
4-hydroxybenzoate polyprenyltransferaseBB451_03950Not AvailablePositive1392574 - 139345832915.2
hypothetical proteinBB451_03955Not AvailablePositive1393451 - 139394518982.3
hypothetical proteinBB451_03960Not AvailablePositive1393958 - 139446419729.8
phosphatidylserine decarboxylaseBB451_03965Not AvailablePositive1394458 - 139526130137.3
quinolinate synthetaseBB451_03970Not AvailablePositive1395251 - 139626137807.7

Displaying genes 1261 – 1270 of 1519 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total