Helicobacter pylori str. 3004

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 3004 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and singular cell arrangement. This organism thrives optimally at 37.0°C, which aligns with the average human body temperature, suggesting its adaptation to a host-associated habitat. Helicobacter pylori is known for its colonization of the gastric mucosa, where it plays a significant role in gastrointestinal microbiota. The microaerophilic nature of H. pylori indicates that it requires reduced oxygen levels for growth, which is consistent with its habitat within the gastric environment, where oxygen is limited. The Gram-negative cell wall structure of this bacterium, characterized by a thin peptidoglycan layer surrounded by an outer membrane, may contribute to its resilience in the acidic conditions of the stomach. Given its specific adaptations, including optimal growth temperature and oxygen requirements, H. pylori strain 3004 exemplifies the intricate relationship between microbial physiology and its ecological niche within the host. Understanding these traits is essential for further studies on its role in the human microbiome and potential implications for digestive health.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strain3004

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. 3004
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 3004 scaffold_9, whole genome shotgun

Gene Summary

Adenine Count

512413 bp

Thymine Count

519941 bp

Guanine Count

327090 bp

Cytosine Count

328342 bp

Genome Length

1687786 bp

Protein-coding Genes

1498 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinBB459_05270Not AvailableNegative682956 - 68357623697.7
hypothetical proteinBB459_05275Not AvailablePositive683678 - 6839329497.8
isoleucine--trna ligaseBB459_05280Not AvailablePositive683957 - 686719106037.0
conjugal transfer protein trbbBB459_05285Not AvailablePositive686736 - 68765034512.5
escn/yscn/hrcn family type iii secretion system atpaseBB459_05290Not AvailablePositive687651 - 68895547637.1
flagellar export apparatus protein fliqBB459_05295Not AvailablePositive688966 - 6892329762.84
udp-n-acetylenolpyruvoylglucosamine reductaseBB459_05300Not AvailablePositive689236 - 69001528686.7
dna (cytosine-5-)-methyltransferaseBB459_05305Not AvailablePositive690346 - 69132037301.6
hypothetical proteinBB459_05310Not AvailablePositive691301 - 69191523596.8
lipopolysaccharide 1,2-glucosyltransferaseBB459_05315Not AvailableNegative692196 - 69329942915.2

Displaying genes 641 – 650 of 1540 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total