Helicobacter pylori str. 3004

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 3004 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and singular cell arrangement. This organism thrives optimally at 37.0°C, which aligns with the average human body temperature, suggesting its adaptation to a host-associated habitat. Helicobacter pylori is known for its colonization of the gastric mucosa, where it plays a significant role in gastrointestinal microbiota. The microaerophilic nature of H. pylori indicates that it requires reduced oxygen levels for growth, which is consistent with its habitat within the gastric environment, where oxygen is limited. The Gram-negative cell wall structure of this bacterium, characterized by a thin peptidoglycan layer surrounded by an outer membrane, may contribute to its resilience in the acidic conditions of the stomach. Given its specific adaptations, including optimal growth temperature and oxygen requirements, H. pylori strain 3004 exemplifies the intricate relationship between microbial physiology and its ecological niche within the host. Understanding these traits is essential for further studies on its role in the human microbiome and potential implications for digestive health.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strain3004

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. 3004
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 3004 scaffold_9, whole genome shotgun

Gene Summary

Adenine Count

512413 bp

Thymine Count

519941 bp

Guanine Count

327090 bp

Cytosine Count

328342 bp

Genome Length

1687786 bp

Protein-coding Genes

1498 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
abc transporter permeaseBB459_02445Not AvailableNegative1376005 - 137700337081.9
Trna-alaNot AvailableNot AvailablePositive1377129 - 1377204Not Available
hypothetical proteinBB459_02455Not AvailablePositive1377363 - 137882053284.7
hypothetical proteinBB459_02460Not AvailablePositive1378833 - 138024251818.9
adenylosuccinate synthaseBB459_02465Not AvailablePositive1380343 - 138157845819.2
flagellar flij family proteinBB459_02470Not AvailablePositive1381575 - 138200316718.5
flagellar proteinBB459_02475Not AvailablePositive1381996 - 138266425106.5
rip metalloprotease rsepBB459_02480Not AvailablePositive1382661 - 138371638958.9
exodeoxyribonuclease vii large subunitBB459_02485Not AvailablePositive1383729 - 138499147142.2
dna methyltransferaseBB459_02490Not AvailableNegative1385010 - 138616444592.9

Displaying genes 1271 – 1280 of 1540 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total