Helicobacter pylori str. 3004

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 3004 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and singular cell arrangement. This organism thrives optimally at 37.0°C, which aligns with the average human body temperature, suggesting its adaptation to a host-associated habitat. Helicobacter pylori is known for its colonization of the gastric mucosa, where it plays a significant role in gastrointestinal microbiota. The microaerophilic nature of H. pylori indicates that it requires reduced oxygen levels for growth, which is consistent with its habitat within the gastric environment, where oxygen is limited. The Gram-negative cell wall structure of this bacterium, characterized by a thin peptidoglycan layer surrounded by an outer membrane, may contribute to its resilience in the acidic conditions of the stomach. Given its specific adaptations, including optimal growth temperature and oxygen requirements, H. pylori strain 3004 exemplifies the intricate relationship between microbial physiology and its ecological niche within the host. Understanding these traits is essential for further studies on its role in the human microbiome and potential implications for digestive health.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strain3004

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. 3004
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 3004 scaffold_9, whole genome shotgun

Gene Summary

Adenine Count

512413 bp

Thymine Count

519941 bp

Guanine Count

327090 bp

Cytosine Count

328342 bp

Genome Length

1687786 bp

Protein-coding Genes

1498 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
disulfide isomeraseBB459_02345Not AvailablePositive1357161 - 135795829532.9
hypothetical proteinBB459_02350Not AvailablePositive1357974 - 135862122962.8
glutathionylspermidine synthaseBB459_02355Not AvailablePositive1358643 - 135981545333.7
hypothetical proteinBB459_02360Not AvailablePositive1359815 - 136034520217.6
sel1 repeat protein hcpeBB459_02365Not AvailableNegative1360793 - 136186039552.3
cytochrome c oxidase subunit iiiBB459_02370Not AvailableNegative1361953 - 136231813966.2
hydroxymethylbilane synthaseBB459_02375Not AvailableNegative1362318 - 136323833895.7
proline--trna ligaseBB459_02380Not AvailableNegative1363249 - 136498265134.4
glutamyl-trna reductaseBB459_02385Not AvailableNegative1364986 - 136633551627.8
polyprenyl synthetaseBB459_02390Not AvailableNegative1366335 - 136725835205.9

Displaying genes 1251 – 1260 of 1540 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total