Helicobacter pylori str. 26100

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori str. 26100 is a Gram-negative bacterium characterized by its spirilla shape and arrangement in singles. This microbe is microaerophilic, requiring a reduced oxygen environment for optimal growth, which aligns with its adaptation to the gastric niche of its host. The optimal growth temperature for H. pylori str. 26100 is approximately 37.0°C, which is consistent with the typical body temperature of mammals, particularly humans, where this organism is primarily found. H. pylori str. 26100 is host-associated, suggesting a specialized ecological niche within the gastrointestinal tract, where it may play a role in various gastric processes. The microaerophilic nature of this organism indicates that it thrives in environments with lower levels of oxygen than are found in the atmosphere, facilitating its survival in the highly acidic conditions of the stomach. The specific adaptation to a host-associated habitat and its microaerophilic requirement may reflect evolutionary pressures that have shaped its metabolic pathways and interactions within the gastric environment. Understanding these traits can provide insights into the ecological dynamics of H. pylori, as well as its potential implications for gastric health and disease in its host organisms.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strain26100

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. 26100
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 26100 scaffold_9, whole genome shotgun

Gene Summary

Adenine Count

517756 bp

Thymine Count

508085 bp

Guanine Count

332684 bp

Cytosine Count

319837 bp

Genome Length

1678362 bp

Protein-coding Genes

1459 genes

Non-Coding Genes

48 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinBB384_00200Not AvailableNegative37404 - 376137636.08
1-pyrroline-5-carboxylate dehydrogenaseBB384_00205Not AvailablePositive37935 - 41492135083.0
sodium/proline symporterBB384_00210Not AvailablePositive41519 - 4300954127.4
hypothetical proteinBB384_00215Not AvailablePositive43051 - 4334111021.4
dna (cytosine-5-)-methyltransferaseBB384_00220Not AvailablePositive43655 - 4420620733.6
dna methyltransferaseBB384_00225Not AvailablePositive44203 - 4490127151.0
agmatine deiminaseBB384_00230Not AvailablePositive44953 - 4594537713.3
carbamoyltransferase hypfBB384_00235Not AvailablePositive45942 - 4819484994.9
hydrogenase expression/formation protein hypeBB384_00240Not AvailablePositive48197 - 4919536432.6
gdp-fucose synthetaseBB384_00245Not AvailableNegative50026 - 5095834917.6

Displaying genes 41 – 50 of 1507 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total