Helicobacter pylori str. 228/99

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 228/99 is a Gram-negative bacterium characterized by its spiral shape and typically exists as single cells. This microbe is adapted to a microaerophilic environment, thriving optimally at a temperature of 37.0°C, which aligns with its habitat as a host-associated organism. The unique morphology of H. pylori, combined with its specific growth requirements, suggests a specialized adaptation to the gastric environment of its host. The microaerophilic nature indicates that it requires reduced oxygen levels for optimal growth, which is consistent with the low-oxygen conditions often found in the stomach. This adaptation may play a crucial role in its survival and colonization within the gastric mucosa, where it may influence the local microbial ecosystem. H. pylori strain 228/99's ability to thrive in such a niche environment underscores its potential role in shaping the gastric microbiome and suggests a complex interplay with host physiology. Understanding these traits may provide insights into the ecological dynamics of this microbe within its host and its potential implications for gastric health.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strain228/99

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. 228/99
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 228/99 Contig54, whole genome shotgun

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

Not Available

Non-Coding Genes

Not Available

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
signal peptidaseHPY228_03800Not AvailablePositive781557 - 78242933769.8
peptidase m50HPY228_03805Not AvailablePositive782438 - 78313626005.8
ribose 5-phosphate isomeraseHPY228_03810Not AvailablePositive783170 - 78363117054.8
membrane proteinHPY228_03815Not AvailablePositive783676 - 78400813013.1
adenine phosphoribosyltransferaseHPY228_03820Not AvailablePositive784066 - 78460519816.6
membrane proteinHPY228_03825Not AvailablePositive784620 - 78519822214.9
aminopeptidase aHPY228_03830Not AvailablePositive785246 - 78673654408.1
gtp-binding proteinHPY228_03835Not AvailablePositive786738 - 78783840580.8
fe-s oxidoreductaseHPY228_03840Not AvailablePositive787868 - 78874033234.0
membrane proteinHPY228_03845Not AvailableNegative788872 - 78991839717.9

Displaying genes 741 – 750 of 1531 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total