Helicobacter pylori str. 228/99

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 228/99 is a Gram-negative bacterium characterized by its spiral shape and typically exists as single cells. This microbe is adapted to a microaerophilic environment, thriving optimally at a temperature of 37.0°C, which aligns with its habitat as a host-associated organism. The unique morphology of H. pylori, combined with its specific growth requirements, suggests a specialized adaptation to the gastric environment of its host. The microaerophilic nature indicates that it requires reduced oxygen levels for optimal growth, which is consistent with the low-oxygen conditions often found in the stomach. This adaptation may play a crucial role in its survival and colonization within the gastric mucosa, where it may influence the local microbial ecosystem. H. pylori strain 228/99's ability to thrive in such a niche environment underscores its potential role in shaping the gastric microbiome and suggests a complex interplay with host physiology. Understanding these traits may provide insights into the ecological dynamics of this microbe within its host and its potential implications for gastric health.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strain228/99

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. 228/99
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 228/99 Contig54, whole genome shotgun

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

Not Available

Non-Coding Genes

Not Available

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
gtpaseHPY228_00175Not AvailableNegative33730 - 3418216752.2
pseudouridine synthaseHPY228_00180Not AvailablePositive34316 - 3529937712.6
Ncrna_class:rnase_p_rnaNot AvailableNot AvailablePositive34804 - 35121Not Available
fibronectinHPY228_00185Not AvailablePositive35262 - 3650947479.4
trna (guanine-n7)-methyltransferaseHPY228_00190Not AvailablePositive36520 - 3770145678.6
abc transporter atp-binding proteinHPY228_00195Not AvailablePositive37698 - 3836925403.8
cell division protein ftsxHPY228_00200Not AvailablePositive38356 - 3916230837.6
peptidase m23HPY228_00205Not AvailablePositive39155 - 4035745988.0
flagellar protein flagHPY228_00210Not AvailablePositive40450 - 4080913407.1
flagellar capping proteinHPY228_00215Not AvailablePositive40826 - 4288374196.8

Displaying genes 51 – 60 of 1531 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total