Helicobacter pylori str. 228/99

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 228/99 is a Gram-negative bacterium characterized by its spiral shape and typically exists as single cells. This microbe is adapted to a microaerophilic environment, thriving optimally at a temperature of 37.0°C, which aligns with its habitat as a host-associated organism. The unique morphology of H. pylori, combined with its specific growth requirements, suggests a specialized adaptation to the gastric environment of its host. The microaerophilic nature indicates that it requires reduced oxygen levels for optimal growth, which is consistent with the low-oxygen conditions often found in the stomach. This adaptation may play a crucial role in its survival and colonization within the gastric mucosa, where it may influence the local microbial ecosystem. H. pylori strain 228/99's ability to thrive in such a niche environment underscores its potential role in shaping the gastric microbiome and suggests a complex interplay with host physiology. Understanding these traits may provide insights into the ecological dynamics of this microbe within its host and its potential implications for gastric health.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strain228/99

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. 228/99
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 228/99 Contig54, whole genome shotgun

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

Not Available

Non-Coding Genes

Not Available

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
polyketide cyclaseHPY228_02290Not AvailablePositive459591 - 46009419441.1
3-hydroxyacid dehydrogenaseHPY228_02295Not AvailablePositive460109 - 46096630802.9
nad(p)h nitroreductaseHPY228_02300Not AvailablePositive460968 - 46162125328.4
glutamate--trna ligaseHPY228_02305Not AvailablePositive461786 - 46310550945.8
membrane proteinHPY228_02310Not AvailablePositive463102 - 46339511134.3
lytic murein transglycosylaseHPY228_02315Not AvailablePositive463404 - 46508665364.7
utp--glucose-1-phosphate uridylyltransferaseHPY228_02320Not AvailablePositive465083 - 46590431002.5
hypothetical proteinHPY228_02325Not AvailablePositive465916 - 46632315668.1
udp-n-acetylglucosamine 1-carboxyvinyltransferaseHPY228_02330Not AvailablePositive466326 - 46759445713.1
aspartate ammonia-lyaseHPY228_02335Not AvailablePositive467652 - 46905851941.9

Displaying genes 451 – 460 of 1531 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total