Helicobacter pylori str. 228/99

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 228/99 is a Gram-negative bacterium characterized by its spiral shape and typically exists as single cells. This microbe is adapted to a microaerophilic environment, thriving optimally at a temperature of 37.0°C, which aligns with its habitat as a host-associated organism. The unique morphology of H. pylori, combined with its specific growth requirements, suggests a specialized adaptation to the gastric environment of its host. The microaerophilic nature indicates that it requires reduced oxygen levels for optimal growth, which is consistent with the low-oxygen conditions often found in the stomach. This adaptation may play a crucial role in its survival and colonization within the gastric mucosa, where it may influence the local microbial ecosystem. H. pylori strain 228/99's ability to thrive in such a niche environment underscores its potential role in shaping the gastric microbiome and suggests a complex interplay with host physiology. Understanding these traits may provide insights into the ecological dynamics of this microbe within its host and its potential implications for gastric health.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strain228/99

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. 228/99
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 228/99 Contig54, whole genome shotgun

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

Not Available

Non-Coding Genes

Not Available

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
l-lactate permeaseHPY228_01795Not AvailablePositive366203 - 36785259272.4
l-lactate permeaseHPY228_01800Not AvailablePositive367903 - 36955859500.5
dna glycosylaseHPY228_01805Not AvailableNegative369582 - 37045132995.5
abc transporter permeaseHPY228_01810Not AvailableNegative370569 - 37201752447.1
cbb3-type cytochrome c oxidase subunit iHPY228_01815Not AvailablePositive372187 - 37365356073.2
peptidase s13HPY228_01820Not AvailablePositive373666 - 37436426525.8
cytochrome b561HPY228_01825Not AvailablePositive374375 - 3745938607.4
cytochrome cbb3HPY228_01830Not AvailablePositive374595 - 37547332522.0
hypothetical proteinHPY228_01835Not AvailablePositive375484 - 3756907790.58
hypothetical proteinHPY228_01840Not AvailablePositive375791 - 37637822221.4

Displaying genes 371 – 380 of 1531 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total