Helicobacter pylori str. 22371

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori str. 22371 is a Gram-negative bacterium characterized by its spirilla shape and solitary cell arrangement. This microbe thrives optimally at a temperature of 37.0°C, which aligns with its habitat as a host-associated organism, typically found in the gastric environment of mammals. H. pylori str. 22371 exhibits microaerophilic oxygen requirements, indicating that it thrives in environments with reduced oxygen levels, which is consistent with the low-oxygen conditions present in the gastric mucosa. The adaptation of H. pylori str. 22371 to its microaerophilic lifestyle suggests a specialized metabolic capability that allows it to survive and maintain its physiological functions in the gastric niche. This adaptation may play a crucial role in its interactions with the host's immune system and gastric environment, potentially influencing the microbial community dynamics within the stomach. Understanding the specific traits of H. pylori str. 22371 can provide valuable insights into its ecological role and the broader implications of its presence in the host's microbiome.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strain22371

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. 22371
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 22371 scaffold_99, whole genome shotgun

Gene Summary

Adenine Count

517477 bp

Thymine Count

515127 bp

Guanine Count

326668 bp

Cytosine Count

334133 bp

Genome Length

1693405 bp

Protein-coding Genes

1478 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
dnaj family proteinBB401_03380Not AvailableNegative425204 - 42607032869.0
hypothetical proteinBB401_03385Not AvailablePositive426238 - 42748846723.9
5'-3' exonucleaseBB401_03390Not AvailableNegative427728 - 42850430335.7
hypothetical proteinBB401_03395Not AvailableNegative428815 - 42971135042.3
bifunctional 2-c-methyl-d-erythritol 4-phosphate cytidylyltransferase/2-c-methyl-d-erythritol 2,4-cyclodiphosphate synthaseBB401_03400Not AvailableNegative429734 - 43095445312.9
serine proteaseBB401_03405Not AvailableNegative430976 - 43240651611.1
s-methylmethionine transporterBB401_03410Not AvailableNegative432451 - 43387852322.0
hypothetical proteinBB401_03420Not AvailablePositive434702 - 4349087213.23
hypothetical proteinBB401_03425Not AvailablePositive434930 - 4351307434.42
hypothetical proteinBB401_03430Not AvailableNegative435376 - 43614628952.5

Displaying genes 371 – 380 of 1520 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total