Helicobacter pylori str. 22371

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori str. 22371 is a Gram-negative bacterium characterized by its spirilla shape and solitary cell arrangement. This microbe thrives optimally at a temperature of 37.0°C, which aligns with its habitat as a host-associated organism, typically found in the gastric environment of mammals. H. pylori str. 22371 exhibits microaerophilic oxygen requirements, indicating that it thrives in environments with reduced oxygen levels, which is consistent with the low-oxygen conditions present in the gastric mucosa. The adaptation of H. pylori str. 22371 to its microaerophilic lifestyle suggests a specialized metabolic capability that allows it to survive and maintain its physiological functions in the gastric niche. This adaptation may play a crucial role in its interactions with the host's immune system and gastric environment, potentially influencing the microbial community dynamics within the stomach. Understanding the specific traits of H. pylori str. 22371 can provide valuable insights into its ecological role and the broader implications of its presence in the host's microbiome.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strain22371

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. 22371
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 22371 scaffold_99, whole genome shotgun

Gene Summary

Adenine Count

517477 bp

Thymine Count

515127 bp

Guanine Count

326668 bp

Cytosine Count

334133 bp

Genome Length

1693405 bp

Protein-coding Genes

1478 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
imp dehydrogenaseBB401_06795Not AvailableNegative1348929 - 135037451874.2
glutaminyl-trna synthase (glutamine-hydrolyzing) subunit aBB401_06800Not AvailableNegative1350384 - 135174549715.4
dephospho-coa kinaseBB401_06805Not AvailableNegative1351805 - 135239522925.3
spermidine synthaseBB401_06810Not AvailableNegative1352397 - 135318530636.4
hypothetical proteinBB401_06815Not AvailableNegative1353277 - 135416734681.0
ribosome biogenesis gtpase derBB401_06820Not AvailablePositive1354244 - 135563251874.3
dna-binding proteinBB401_06825Not AvailablePositive1355885 - 135616910409.4
Trna-argNot AvailableNot AvailablePositive1356233 - 1356309Not Available
3-methyladenine dna glycosylaseBB401_06835Not AvailableNegative1356560 - 135721625241.7
flagellin bBB401_06840Not AvailableNegative1357335 - 135886753287.6

Displaying genes 1231 – 1240 of 1520 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total