Helicobacter pylori str. 22368

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 22368 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and single-cell arrangement. This organism thrives optimally at a temperature of 37.0°C, suggesting its adaptation to the warm environment of the human gastric niche. As a host-associated microbe, Helicobacter pylori strain 22368 is commonly found in the stomach lining of its hosts, where it plays a role in complex interactions with the gastric environment. The microaerophilic nature of Helicobacter pylori indicates that it requires reduced levels of oxygen for growth, which aligns with its habitat within the human stomach, where oxygen concentration is lower than in the atmosphere. The unique morphological characteristics of this bacterium, combined with its physiological requirements, underscore its specialization for survival in the gastric ecosystem. Given its adaptation to a highly specific environment, Helicobacter pylori strain 22368 may be influenced by the host's diet and gastric secretions, making it an intriguing subject for studying host-microbe interactions. This strain serves as a model for understanding the complexities of microbial life in acidic environments and highlights the importance of microbial adaptations in maintaining ecological balance within host-associated habitats.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strain22368

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. 22368
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 22368 scaffold_9, whole genome shotgun

Gene Summary

Adenine Count

498891 bp

Thymine Count

510619 bp

Guanine Count

314876 bp

Cytosine Count

327778 bp

Genome Length

1652164 bp

Protein-coding Genes

1481 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Trna-glnNot AvailableNot AvailablePositive391820 - 391894Not Available
Trna-metNot AvailableNot AvailablePositive391921 - 391997Not Available
hypothetical proteinBB403_04495Not AvailablePositive392425 - 39431767730.5
hypothetical proteinBB403_04500Not AvailablePositive394429 - 3945936067.77
disulfide bond formation protein dsbbBB403_04505Not AvailablePositive394602 - 39607455243.8
tumor necrosis factor alpha-inducing proteinBB403_04515Not AvailablePositive396548 - 39712621849.6
penicillin-binding proteinBB403_04520Not AvailableNegative397129 - 39911174300.7
8-amino-7-oxononanoate synthaseBB403_04525Not AvailableNegative399112 - 40023342105.0
hemolysinBB403_04530Not AvailableNegative400256 - 40155748250.9
multidrug resistance proteinBB403_04535Not AvailableNegative401629 - 40341068408.0

Displaying genes 361 – 370 of 1523 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total