Helicobacter pylori str. 22352

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori str. 22352 is a Gram-negative bacterium characterized by its spiral shape and occurrence as single cells. This microbe is classified as microaerophilic, indicating that it thrives in environments with reduced oxygen levels, which aligns with its habitat as a host-associated organism. The optimal growth temperature for H. pylori str. 22352 is approximately 37.0°C, a condition that is typically found in the human stomach, suggesting a specialized adaptation to its niche. The spiral morphology of H. pylori is significant for its motility, allowing the bacterium to navigate through the viscous gastric mucus and colonize the gastric epithelium. This adaptation is crucial for its survival in the acidic environment of the stomach, where it can evade the host's immune responses and establish a persistent infection. In terms of its ecological role, H. pylori str. 22352 may contribute to the complex microbial community of the gastric microbiome. The interactions between this bacterium and other microbial inhabitants could influence not only gastric health but also broader implications for host metabolism and immune regulation. Understanding the specific traits of H. pylori str. 22352 enhances our comprehension of its ecological dynamics and potential impact within the host environment.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strain22352

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. 22352
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 22352 contig_9, whole genome shotgun

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

1481 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
dna-binding response regulatorBB409_05100Not AvailablePositive757911 - 75858825857.0
two-component sensor histidine kinaseBB409_05105Not AvailablePositive758612 - 75986949272.4
nicotinate-nucleotide diphosphorylase (carboxylating)BB409_05110Not AvailablePositive759870 - 76067330095.4
hypothetical proteinBB409_05115Not AvailableNegative761234 - 76257452444.8
hypothetical proteinBB409_05120Not AvailableNegative762585 - 76291412448.9
nadph-dependent 7-cyano-7-deazaguanine reductase quefBB409_05125Not AvailableNegative762990 - 76343617041.6
ribosome silencing factorBB409_05130Not AvailablePositive763495 - 76383613012.7
trna (adenosine(37)-n6)-dimethylallyltransferase miaaBB409_05135Not AvailablePositive763907 - 76474031520.2
lipopolysaccharide 1,2-glucosyltransferaseBB409_05140Not AvailablePositive764741 - 76584442950.2
sulfataseBB409_05145Not AvailablePositive765854 - 76666330560.9

Displaying genes 711 – 720 of 1523 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total