Helicobacter pylori str. 22352

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori str. 22352 is a Gram-negative bacterium characterized by its spiral shape and occurrence as single cells. This microbe is classified as microaerophilic, indicating that it thrives in environments with reduced oxygen levels, which aligns with its habitat as a host-associated organism. The optimal growth temperature for H. pylori str. 22352 is approximately 37.0°C, a condition that is typically found in the human stomach, suggesting a specialized adaptation to its niche. The spiral morphology of H. pylori is significant for its motility, allowing the bacterium to navigate through the viscous gastric mucus and colonize the gastric epithelium. This adaptation is crucial for its survival in the acidic environment of the stomach, where it can evade the host's immune responses and establish a persistent infection. In terms of its ecological role, H. pylori str. 22352 may contribute to the complex microbial community of the gastric microbiome. The interactions between this bacterium and other microbial inhabitants could influence not only gastric health but also broader implications for host metabolism and immune regulation. Understanding the specific traits of H. pylori str. 22352 enhances our comprehension of its ecological dynamics and potential impact within the host environment.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strain22352

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. 22352
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 22352 contig_9, whole genome shotgun

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

1481 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
transcriptional regulatorBB409_03440Not AvailableNegative432139 - 43286127087.3
delta-aminolevulinic acid dehydrataseBB409_03445Not AvailableNegative432862 - 43383336213.0
hypothetical proteinBB409_03455Not AvailableNegative434620 - 43503615552.2
caldesmonBB409_03460Not AvailablePositive435325 - 43661750347.0
methionyl-trna formyltransferaseBB409_03470Not AvailablePositive439284 - 44019533921.0
biotin--[acetyl-coa-carboxylase] ligaseBB409_03475Not AvailablePositive440192 - 44083023942.0
sporulation initiation inhibitor sojBB409_03480Not AvailablePositive440836 - 44162729067.6
chromosome partitioning protein parbBB409_03485Not AvailablePositive441630 - 44250233420.6
atp f0f1 synthase subunit b'BB409_03490Not AvailablePositive442640 - 44304715553.8
atp f0f1 synthase subunit bBB409_03495Not AvailablePositive443051 - 44356619843.7

Displaying genes 401 – 410 of 1523 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total