Helicobacter pylori str. 22352

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori str. 22352 is a Gram-negative bacterium characterized by its spiral shape and occurrence as single cells. This microbe is classified as microaerophilic, indicating that it thrives in environments with reduced oxygen levels, which aligns with its habitat as a host-associated organism. The optimal growth temperature for H. pylori str. 22352 is approximately 37.0°C, a condition that is typically found in the human stomach, suggesting a specialized adaptation to its niche. The spiral morphology of H. pylori is significant for its motility, allowing the bacterium to navigate through the viscous gastric mucus and colonize the gastric epithelium. This adaptation is crucial for its survival in the acidic environment of the stomach, where it can evade the host's immune responses and establish a persistent infection. In terms of its ecological role, H. pylori str. 22352 may contribute to the complex microbial community of the gastric microbiome. The interactions between this bacterium and other microbial inhabitants could influence not only gastric health but also broader implications for host metabolism and immune regulation. Understanding the specific traits of H. pylori str. 22352 enhances our comprehension of its ecological dynamics and potential impact within the host environment.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strain22352

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. 22352
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 22352 contig_9, whole genome shotgun

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

1481 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
sodium:calcium antiporterBB409_07010Not AvailableNegative1265370 - 126651541535.5
sodium:calcium antiporterBB409_07015Not AvailableNegative1266526 - 126747033865.4
hypothetical proteinBB409_07020Not AvailablePositive1267457 - 12676576758.37
sodium:calcium antiporterBB409_07025Not AvailableNegative1267654 - 126808216001.2
sodium:calcium antiporterBB409_07030Not AvailableNegative1268137 - 126894331804.4
transporterBB409_07035Not AvailableNegative1268945 - 1271896112010.0
sodium:calcium antiporterBB409_07040Not AvailableNegative1271905 - 127252824051.2
sodium:calcium antiporterBB409_07045Not AvailableNegative1272530 - 127287712002.0
cag pathogenicity island proteinBB409_07050Not AvailableNegative1273020 - 12732479031.12
4-hydroxy-tetrahydrodipicolinate reductaseBB409_07055Not AvailableNegative1273695 - 127445927899.0

Displaying genes 1171 – 1180 of 1523 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total