Helicobacter pylori str. 22315

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 22315 is a Gram-negative, microaerophilic bacterium characterized by its spiral shape and single-cell arrangement. This organism thrives optimally at a temperature of 37.0°C, which aligns with its habitat as a host-associated microbe, commonly found in the human gastric environment. As a member of the Helicobacter genus, strain 22315 is adapted to survive in the acidic conditions of the stomach, utilizing its unique morphology and metabolic capabilities. The microaerophilic nature of H. pylori suggests a specialized adaptation to low-oxygen environments, which is essential for its survival in the gastric niche. The ecological role of Helicobacter pylori, particularly strain 22315, can be inferred from its habitat and characteristics. This bacterium is not only notable for its interaction with the human host but also for its potential influence on gastric microbiota and host physiology. Understanding the precise adaptations of strain 22315 enhances our comprehension of its ecological dynamics and potential implications for host health in the context of gastric environments.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strain22315

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. 22315
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 22315 scaffold_9, whole genome shotgun

Gene Summary

Adenine Count

507282 bp

Thymine Count

508450 bp

Guanine Count

321470 bp

Cytosine Count

324612 bp

Genome Length

1661814 bp

Protein-coding Genes

1472 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
peptidase m23BB425_00190Not AvailableNegative34749 - 3568735626.3
peptidase m23BB425_00195Not AvailableNegative35697 - 3662334897.5
bifunctional folylpolyglutamate synthase/dihydrofolate synthaseBB425_00200Not AvailableNegative36623 - 3779244566.3
hypothetical proteinBB425_00205Not AvailableNegative37782 - 3829419596.2
leucine--trna ligaseBB425_00210Not AvailableNegative38291 - 4071193060.0
hypothetical proteinBB425_00215Not AvailableNegative40721 - 4105912230.5
protein-export membrane protein secfBB425_00220Not AvailableNegative41069 - 4204036191.0
protein-export membrane protein secdBB425_00225Not AvailableNegative42049 - 4362956844.4
preprotein translocase subunit yajcBB425_00230Not AvailableNegative43630 - 4392311167.7
na+/h+ antiporter nhaaBB425_00235Not AvailableNegative43971 - 4528747841.1

Displaying genes 41 – 50 of 1514 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total