Helicobacter pylori str. 2061

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 2061 is a Gram-negative, microaerophilic bacterium characterized by its spiral shape and solitary cell arrangement. This strain thrives optimally at a temperature of 37.0°C, which aligns with the typical conditions found in the gastric environment of its host. As a member of the Helicobacter genus, H. pylori is primarily associated with the gastric mucosa of humans and other animals, where it is known to inhabit the acidic environment of the stomach. The microaerophilic nature of this organism allows it to survive in environments with reduced oxygen levels, which is essential for its colonization and persistence in the host's gastric milieu. Given its specific habitat and physiological requirements, H. pylori strain 2061 may play a significant role in shaping the microbial community within the gastric niche. Its ability to adapt to the harsh conditions of the stomach, including the presence of gastric acid, provides insights into microbial survival strategies in extreme environments. This adaptability underscores the importance of H. pylori in understanding host-microbe interactions and the complexities of gastrointestinal microbiota.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strain2061

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. 2061
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 2061 scaffold_9, whole genome shotgun

Gene Summary

Adenine Count

491456 bp

Thymine Count

487179 bp

Guanine Count

319348 bp

Cytosine Count

308731 bp

Genome Length

1606714 bp

Protein-coding Genes

1443 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
pyruvate ferredoxin oxidoreductaseBB461_07345Not AvailablePositive1055120 - 105606435003.9
adenylosuccinate lyaseBB461_07350Not AvailablePositive1056173 - 105749550005.5
hypothetical proteinBB461_07355Not AvailablePositive1057560 - 105839331654.7
excinuclease abc subunit bBB461_07360Not AvailableNegative1058390 - 106036676008.7
competence protein comgfBB461_07375Not AvailablePositive1061144 - 106236447174.2
cell filamentation protein ficBB461_07380Not AvailablePositive1062364 - 106306827411.2
rna polymerase factor sigma-54BB461_07385Not AvailableNegative1063080 - 106432448254.2
lps export abc transporter atp-binding proteinBB461_07390Not AvailableNegative1064327 - 106504926443.1
trna (n6-adenosine(37)-n6)-threonylcarbamoyltransferase complex atpase tsaeBB461_07395Not AvailableNegative1065062 - 106546315004.5
dna polymerase iii subunit gamma/tauBB461_07400Not AvailableNegative1065460 - 106726268342.0

Displaying genes 981 – 990 of 1485 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total