Helicobacter pylori str. 2061

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 2061 is a Gram-negative, microaerophilic bacterium characterized by its spiral shape and solitary cell arrangement. This strain thrives optimally at a temperature of 37.0°C, which aligns with the typical conditions found in the gastric environment of its host. As a member of the Helicobacter genus, H. pylori is primarily associated with the gastric mucosa of humans and other animals, where it is known to inhabit the acidic environment of the stomach. The microaerophilic nature of this organism allows it to survive in environments with reduced oxygen levels, which is essential for its colonization and persistence in the host's gastric milieu. Given its specific habitat and physiological requirements, H. pylori strain 2061 may play a significant role in shaping the microbial community within the gastric niche. Its ability to adapt to the harsh conditions of the stomach, including the presence of gastric acid, provides insights into microbial survival strategies in extreme environments. This adaptability underscores the importance of H. pylori in understanding host-microbe interactions and the complexities of gastrointestinal microbiota.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strain2061

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. 2061
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 2061 scaffold_9, whole genome shotgun

Gene Summary

Adenine Count

491456 bp

Thymine Count

487179 bp

Guanine Count

319348 bp

Cytosine Count

308731 bp

Genome Length

1606714 bp

Protein-coding Genes

1443 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinBB461_03215Not AvailablePositive1415455 - 141595819097.4
pantothenate kinaseBB461_03220Not AvailablePositive1416349 - 141667811465.7
hypothetical proteinBB461_03225Not AvailablePositive1416705 - 141721119176.5
ribonucleoside-diphosphate reductase subunit alphaBB461_03230Not AvailablePositive1417377 - 141974390212.9
oxidoreductaseBB461_03235Not AvailablePositive1419804 - 142075135985.1
hypothetical proteinBB461_03240Not AvailablePositive1420864 - 142163127496.6
cysteine methyltransferaseBB461_03245Not AvailablePositive1421635 - 142214119168.2
integraseBB461_03250Not AvailableNegative1422206 - 142327641243.2
hypothetical proteinBB461_03255Not AvailableNegative1423283 - 142519674132.2
aspartate aminotransferaseBB461_03260Not AvailableNegative1425347 - 142651942693.8

Displaying genes 1311 – 1320 of 1485 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total