Helicobacter pylori str. 2036

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori str. 2036 is a Gram-negative bacterium characterized by its spiral shape and single-cell arrangement. This microbe thrives optimally at a temperature of 37.0°C and exhibits microaerophilic growth, indicating a requirement for reduced oxygen levels for its metabolic processes. H. pylori str. 2036 is typically host-associated, suggesting a close relationship with its host environment, which may influence its growth and survival strategies. As a member of the Helicobacter genus, it is important to note that H. pylori is well-studied for its role in the gastric microbiome, particularly its association with the human stomach. The microaerophilic nature of this strain reflects its adaptation to the specific oxygen conditions found within the gastric mucosa, where it can colonize and persist in the presence of acidic conditions. Moreover, the spiral shape of H. pylori str. 2036 may facilitate its motility through the viscous environment of the gastric mucosa, potentially aiding in its colonization and interaction with host tissues. This trait, combined with its optimal temperature and habitat preferences, highlights the specialized ecological niche that H. pylori occupies. Understanding these characteristics can provide insights into the bacterium's behavior and its interactions within its host environment, as well as its potential implications for gastric health.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strain2036

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. 2036
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 2036 scaffold_9, whole genome shotgun

Gene Summary

Adenine Count

504110 bp

Thymine Count

502055 bp

Guanine Count

321126 bp

Cytosine Count

320657 bp

Genome Length

1647948 bp

Protein-coding Genes

1468 genes

Non-Coding Genes

43 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinBB464_04325Not AvailableNegative268491 - 26937232964.5
flagellar motor switch protein flinBB464_04330Not AvailableNegative269369 - 26974013998.9
endonuclease iiiBB464_04335Not AvailableNegative269822 - 27047224378.8
hypothetical proteinBB464_04340Not AvailableNegative270475 - 2707058718.85
hypothetical proteinBB464_04345Not AvailableNegative270702 - 273641111162.0
aminodeoxychorismate lyaseBB464_04350Not AvailablePositive273559 - 27454837590.1
2-oxoglutarate:acceptor oxidoreductaseBB464_04355Not AvailablePositive274733 - 27507412409.2
2-oxoglutarate synthase subunit alphaBB464_04360Not AvailablePositive275074 - 27620141509.3
2-oxoglutarate ferredoxin oxidoreductase subunit betaBB464_04365Not AvailablePositive276203 - 27702430416.3
2-oxoglutarate:acceptor oxidoreductaseBB464_04370Not AvailablePositive277024 - 27757820046.5

Displaying genes 261 – 270 of 1511 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total