Helicobacter pylori str. 2036

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori str. 2036 is a Gram-negative bacterium characterized by its spiral shape and single-cell arrangement. This microbe thrives optimally at a temperature of 37.0°C and exhibits microaerophilic growth, indicating a requirement for reduced oxygen levels for its metabolic processes. H. pylori str. 2036 is typically host-associated, suggesting a close relationship with its host environment, which may influence its growth and survival strategies. As a member of the Helicobacter genus, it is important to note that H. pylori is well-studied for its role in the gastric microbiome, particularly its association with the human stomach. The microaerophilic nature of this strain reflects its adaptation to the specific oxygen conditions found within the gastric mucosa, where it can colonize and persist in the presence of acidic conditions. Moreover, the spiral shape of H. pylori str. 2036 may facilitate its motility through the viscous environment of the gastric mucosa, potentially aiding in its colonization and interaction with host tissues. This trait, combined with its optimal temperature and habitat preferences, highlights the specialized ecological niche that H. pylori occupies. Understanding these characteristics can provide insights into the bacterium's behavior and its interactions within its host environment, as well as its potential implications for gastric health.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strain2036

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. 2036
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 2036 scaffold_9, whole genome shotgun

Gene Summary

Adenine Count

504110 bp

Thymine Count

502055 bp

Guanine Count

321126 bp

Cytosine Count

320657 bp

Genome Length

1647948 bp

Protein-coding Genes

1468 genes

Non-Coding Genes

43 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinBB464_02595Not AvailablePositive1250164 - 125103633941.6
bifunctional aminodeoxychorismate synthase component i/aminotransferaseBB464_02600Not AvailablePositive1251037 - 125271664642.9
acylamide amidohydrolaseBB464_02605Not AvailablePositive1252911 - 125393037764.0
flagellar biosynthesis protein flglBB464_02610Not AvailableNegative1254012 - 125649891888.8
50s ribosomal protein l21BB464_02615Not AvailablePositive1256741 - 125705511851.8
50s ribosomal protein l27BB464_02620Not AvailablePositive1257070 - 12573369707.68
peptide abc transporter substrate-binding proteinBB464_02625Not AvailablePositive1257453 - 125910262290.8
peptide abc transporter permeaseBB464_02630Not AvailablePositive1259113 - 126011736975.4
diguanylate cyclaseBB464_02635Not AvailablePositive1260117 - 126097430851.0
peptide abc transporter atp-binding proteinBB464_02640Not AvailablePositive1260986 - 126184932241.5

Displaying genes 1151 – 1160 of 1511 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total