Helicobacter pylori str. 1039

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 1039 is a Gram-negative, microaerophilic bacterium characterized by its spirilla shape and single-cell arrangement. This organism optimally thrives at 37.0°C, indicating its adaptation to the physiological temperature found within its host. H. pylori is predominantly associated with the gastric mucosa of humans and other hosts, reflecting its evolutionary niche as a host-associated microbe. The microaerophilic nature of H. pylori suggests that it thrives in environments with reduced oxygen levels, which is consistent with the low-oxygen conditions typically found in the stomach. This adaptation not only facilitates its survival but may also play a role in its interactions with the host's immune system. The unique morphology of H. pylori, with its helical shape, likely contributes to its motility within the viscous gastric mucus, aiding in colonization and persistence in the harsh gastric environment. The ecological implications of H. pylori strain 1039's traits underscore the importance of host-associated microbes in influencing gastrointestinal health. The specific adaptations of H. pylori to its microaerophilic habitat and optimal temperature highlight its role in the complex microbial community of the stomach, where it may impact both host physiology and the overall microbial ecology. Understanding these traits could provide insights into the potential roles of H. pylori in health and disease, emphasizing the delicate balance between host and microbial interactions.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strain1039

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. 1039
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 1039 scaffold_9, whole genome shotgun

Gene Summary

Adenine Count

510006 bp

Thymine Count

508402 bp

Guanine Count

327850 bp

Cytosine Count

319376 bp

Genome Length

1665634 bp

Protein-coding Genes

1466 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
dna helicase iiBB482_00800Not AvailableNegative161880 - 16392577642.7
anaphase-promoting proteinBB482_00805Not AvailableNegative163925 - 16646597036.8
serine--trna ligaseBB482_00810Not AvailableNegative166475 - 16772247336.2
exodeoxyribonuclease vii small subunitBB482_00820Not AvailableNegative168524 - 16878410001.8
bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylaseBB482_00825Not AvailableNegative168794 - 16953427927.1
tigr00701 family proteinBB482_00830Not AvailableNegative169561 - 17000717261.0
yigz family proteinBB482_00835Not AvailableNegative170017 - 17058921440.8
antibiotic abc transporter permeaseBB482_00840Not AvailableNegative170576 - 17170642452.8
abc transporterBB482_00845Not AvailableNegative171703 - 17280041118.2
hypothetical proteinBB482_00850Not AvailableNegative172812 - 17378935804.9

Displaying genes 161 – 170 of 1508 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total