Helicobacter pylori str. 1002

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori str. 1002 is a Gram-negative, microaerophilic bacterium characterized by its distinct spirilla shape and arrangement in singles. This organism thrives optimally at a temperature of 37.0°C, which aligns with its habitat within a host-associated environment, typically residing in the gastric mucosa of mammals. The microaerophilic nature of H. pylori str. 1002 suggests that it requires reduced levels of oxygen for growth, which is consistent with the low-oxygen conditions often found in the stomach. The bacterium's spiral form may facilitate its motility through the viscous gastric environment, potentially enhancing its ability to colonize and persist in the highly acidic conditions of the stomach. Given its adaptation to a host-associated habitat and optimal growth temperature, H. pylori str. 1002 likely plays a significant role in the microbial ecology of the gastric environment, contributing to the complex interactions between the host and its microbiota. This relationship highlights the potential influence of H. pylori on gastric health and disease, as its presence and behavior in the host can impact overall digestive functions and host immunity. Further exploration of its ecological role may provide insights into the dynamics of stomach microbiomes and their implications for gastrointestinal health.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strain1002

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori str. 1002
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 1002 scaffold37.1, whole genome shotgun

Gene Summary

Adenine Count

490823 bp

Thymine Count

489787 bp

Guanine Count

319381 bp

Cytosine Count

309946 bp

Genome Length

1612768 bp

Protein-coding Genes

1466 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
bifunctional indole-3-glycerol-phosphate synthase trpc/phosphoribosylanthranilate isomerase trpfEGW00_05155Not AvailableNegative1026113 - 102747150847.3
anthranilate phosphoribosyltransferaseEGW00_05160Not AvailableNegative1027464 - 102847136721.9
aminodeoxychorismate/anthranilate synthase component iiEGW00_05165Not AvailableNegative1028468 - 102905221556.4
anthranilate synthase component iEGW00_05170Not AvailableNegative1029049 - 103055156421.1
lipopolysaccharide heptosyltransferase family proteinEGW00_05175Not AvailableNegative1030720 - 103177839682.3
5'-nucleotidase, lipoprotein e(p4) familyEGW00_05180Not AvailableNegative1031846 - 103258327853.9
polyisoprenoid-binding proteinEGW00_05185Not AvailablePositive1032707 - 103325520585.9
thiaminase iiEGW00_05190Not AvailableNegative1033319 - 103397225052.8
nickel-binding protein hpnlEGW00_05200Not AvailableNegative1035313 - 103557010331.3
16s rrna (adenine(1518)-n(6)/adenine(1519)-n(6))- dimethyltransferase rsmaEGW00_05205Not AvailablePositive1035825 - 103664030573.6

Displaying genes 971 – 980 of 1508 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total