Salmonella enterica subsp. enterica serovar Typhimurium

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Proteobacteria

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Salmonella

Description

Salmonella enterica subsp. enterica serovar Typhimurium is a Gram-negative, rod-shaped bacterium that exhibits motility through the presence of true flagella. This organism is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. As a chemoorganotroph, it derives energy from organic compounds, making it well-suited to its host-associated habitat. S. Typhimurium is mesophilic, with an optimal growth temperature of 37°C, which corresponds to the typical body temperature of many warm-blooded hosts. Its biotic relationship is characterized by being free-living, suggesting a potential for survival outside of host organisms. The bacterium possesses a complex genomic structure, comprising ten replicons, which may contribute to its adaptability and survival in various environments. Understanding the traits of S. Typhimurium not only provides insights into its biological and ecological roles but also highlights its potential implications in food safety and public health, given its association with gastrointestinal infections in humans and animals. The ability to thrive in diverse environments underscores the importance of monitoring this microbe in ecological and clinical contexts.

Taxonomy

KingdomPseudomonadati
PhylumProteobacteria
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusSalmonella
Speciesenterica
StrainTyphimurium

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranesNot Available
Image of Salmonella enterica subsp. enterica serovar Typhimurium
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceChemoorganotroph
PathogenicityNot Available

Gene Summary

Adenine Count

1088 bp

Thymine Count

1132 bp

Guanine Count

1071 bp

Cytosine Count

957 bp

Genome Length

4248 bp

Protein-coding Genes

6 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

10

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
AttlNot AvailableNot AvailablePositive368699 - 368745Not Available
IntegraseSTL3553_RS27830P04890Negative368759 - 36992244832.0
ExcisionaseSTL3553_RS25695P04889Negative369835 - 37014911533.8
Formate dehydrogenase n alpha subunitSTL3553_RS27835Not AvailableNegative370152 - 3702924887.25
Hypothetical proteinSTL3553_RS28060Q03544Negative370630 - 3707554702.75
Putative methylaseSTL3553_RS01670Not AvailableNegative370759 - 37123218069.9
Gene 21 proteinSTL3553_RS01675Not AvailableNegative371361 - 37168111797.8
Hypothetical proteinSTL3553_RS01680Not AvailableNegative371683 - 37198211456.9
Hypothetical proteinSTL3553_RS01685P76515Negative371979 - 37237714279.1
Hypothetical proteinSTL3553_RS01690P11192Negative372374 - 3725386374.91

Displaying genes 1 – 10 of 19841 in total

Metabolites

372 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000399(S)-allantoinC4H6N4O3Chemical structure of (S)-allantoin97-59-6
Average158.1154Da
Monoisotopic158.0439901Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000430hercynineC9H15N3O2Chemical structure of hercynineNot available
Average197.238Da
Monoisotopic197.1164267Da
BASm00005275-oxopentanoateC5H7O3Chemical structure of 5-oxopentanoateNot available
Average115.109Da
Monoisotopic115.040067665Da
BASm0000542HgHgChemical structure of HgNot available
Average200.59Da
Monoisotopic201.9706256Da
BASm0000549cis-1,2-dihydrobenzene-1,2-diolC6H8O2Chemical structure of cis-1,2-dihydrobenzene-1,2-diolNot available
Average112.128Da
Monoisotopic112.0524295Da
BASm0000590phloretateC9H9O3Chemical structure of phloretateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da

Displaying 11–20 of 372 metabolites

Health Effects

Health ConditionRelationReference
GastroenteritisCausesPMC10714929
Invasive infectionsCausesPMC10714929
EnterocolitisCausesPMC6516042
FeverCausesPMC6516042
EnteritisCausesPMC6516042
Food poisoningCausesPMC7885583
SalmonellosisCausesPMC9843761
Food poisoningCausesPMC9843761
Bacterial gastroenteritisCausesPMC11510697
SalmonellosisCausesPMC10685019

Displaying health effects 1 – 10 of 16 in total