Salmonella enterica subsp. enterica serovar Typhimurium

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Proteobacteria

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Salmonella

Description

Salmonella enterica subsp. enterica serovar Typhimurium is a Gram-negative, rod-shaped bacterium that exhibits motility through the presence of true flagella. This organism is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. As a chemoorganotroph, it derives energy from organic compounds, making it well-suited to its host-associated habitat. S. Typhimurium is mesophilic, with an optimal growth temperature of 37°C, which corresponds to the typical body temperature of many warm-blooded hosts. Its biotic relationship is characterized by being free-living, suggesting a potential for survival outside of host organisms. The bacterium possesses a complex genomic structure, comprising ten replicons, which may contribute to its adaptability and survival in various environments. Understanding the traits of S. Typhimurium not only provides insights into its biological and ecological roles but also highlights its potential implications in food safety and public health, given its association with gastrointestinal infections in humans and animals. The ability to thrive in diverse environments underscores the importance of monitoring this microbe in ecological and clinical contexts.

Taxonomy

KingdomPseudomonadati
PhylumProteobacteria
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusSalmonella
Speciesenterica
StrainTyphimurium

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranesNot Available
Image of Salmonella enterica subsp. enterica serovar Typhimurium
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceChemoorganotroph
PathogenicityNot Available

Gene Summary

Adenine Count

39381 bp

Thymine Count

36323 bp

Guanine Count

41365 bp

Cytosine Count

39254 bp

Genome Length

156323 bp

Protein-coding Genes

172 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

10

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
AttlNot AvailableNot AvailablePositive368699 - 368745Not Available
IntegraseSTL3553_RS27830P04890Negative368759 - 36992244832.0
ExcisionaseSTL3553_RS25695P04889Negative369835 - 37014911533.8
Formate dehydrogenase n alpha subunitSTL3553_RS27835Not AvailableNegative370152 - 3702924887.25
Hypothetical proteinSTL3553_RS28060Q03544Negative370630 - 3707554702.75
Putative methylaseSTL3553_RS01670Not AvailableNegative370759 - 37123218069.9
Gene 21 proteinSTL3553_RS01675Not AvailableNegative371361 - 37168111797.8
Hypothetical proteinSTL3553_RS01680Not AvailableNegative371683 - 37198211456.9
Hypothetical proteinSTL3553_RS01685P76515Negative371979 - 37237714279.1
Hypothetical proteinSTL3553_RS01690P11192Negative372374 - 3725386374.91

Displaying genes 1 – 10 of 19841 in total

Metabolites

7 records
Metabolite IDMetabolite nameStructureCAS number
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da
BASm00027107,8-dihydrofolateC19H19N7O6Chemical structure of 7,8-dihydrofolateNot available
Average441.405Da
Monoisotopic441.1407785Da
BASm0002736streptomycin 3''-phosphateC21H41N7O15PChemical structure of streptomycin 3''-phosphateNot available
Average662.566Da
Monoisotopic662.239277066Da
BASm0003389NADP(+)C21H25N7O17P3Chemical structure of NADP(+)Not available
Average740.386Da
Monoisotopic740.053624107Da
BASm00035853''-O-adenylylstreptomycinC31H53N12O18PChemical structure of 3''-O-adenylylstreptomycinNot available
Average912.804Da
Monoisotopic912.332742753Da
BASm0010806spectinomycinC14H24N2O7Chemical structure of spectinomycinNot available
Average332.353Da
Monoisotopic332.1583511Da
BASm00108079-O-adenylylspectinomycinC24H36N7O13PChemical structure of 9-O-adenylylspectinomycinNot available
Average661.562Da
Monoisotopic661.2108712Da

Displaying 1–7 of 7 metabolites

Health Effects

Health ConditionRelationReference
GastroenteritisCausesPMC10714929
Invasive infectionsCausesPMC10714929
EnterocolitisCausesPMC6516042
FeverCausesPMC6516042
EnteritisCausesPMC6516042
Food poisoningCausesPMC7885583
SalmonellosisCausesPMC9843761
Food poisoningCausesPMC9843761
Bacterial gastroenteritisCausesPMC11510697
SalmonellosisCausesPMC10685019

Displaying health effects 1 – 10 of 16 in total