Haemophilus influenzae Rd KW20

Gram-negativeRodNon-motileAerobe; facultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Pasteurellales

Family

Pasteurellaceae

Genus

Haemophilus

Description

Haemophilus influenzae Rd KW20 is a Gram-negative, rod-shaped bacterium that thrives optimally at a temperature of 35-37 °C. As a chemoheterotroph, it derives its energy from organic compounds, relying on the organic matter present in its environment for growth. This microbe is primarily found in the human respiratory tract, specifically in the nasopharynx and can also be isolated from various other body sites, including the ears, lungs, and sinuses. Classified as a facultative anaerobe, it can live in both aerobic and anaerobic conditions, making it adaptable to a range of environments within the host. H. influenzae Rd KW20 is notable for its role in human health; while it is part of the normal flora of the upper respiratory tract in healthy individuals, it can become pathogenic under certain circumstances. It is known to cause a range of infections, including pneumonia, sinusitis, and otitis media, particularly in children and immunocompromised adults.As a strain in the study of bacterial genetics, H. influenzae Rd KW20 has contributed to significant advancements in the understanding of molecular biology and genetics. Remarkably, it was one of the first organisms to have its genome completely sequenced, providing valuable insights into bacterial evolution, pathogenic mechanisms, and antibiotic resistance. Moreover, its relatively simple genetic makeup makes it an ideal model organism for laboratory studies, facilitating research in areas such as gene expression, protein function, and microbial interactions within the host.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderPasteurellales
FamilyPasteurellaceae
GenusHaemophilus
SpeciesHaemophilus influenzae
StrainRd KW20

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Haemophilus influenzae Rd KW20
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe; facultative anaerobe
Optimal temperature35
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityYes

Genome Summary

Haemophilus influenzae Rd KW20

Accession NumberNC_000907.1

Gene Summary

Adenine Count

567623 bp

Thymine Count

564241 bp

Guanine Count

347436 bp

Cytosine Count

350723 bp

Genome Length

1830138 bp

Protein-coding Genes

1663 genes

Non-Coding Genes

140 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
RepHI_RS08070Not Available+1638282 - 163879518732.5
Site-specific integraseHI_RS08075P46495-1638752 - 163972637550.4
Trna-val;Not AvailableNot Available+1639927 - 1640003Not Available
pyruvate kinaseHI_RS08085P43924+1640232 - 164166851057.7
BanHI_RS08090P45256+1641810 - 164321652365.5
AttrNot AvailableNot Available+1650200 - 1650214Not Available
type i glyceraldehyde-3-phosphate dehydrogenaseHI_RS00005P44304+2 - 102136053.9
long-chain fatty acid--coa ligaseHI_RS00010P44446+1214 - 301368713.5
cof-type had-iib family hydrolaseHI_RS00015P44447-3050 - 383529224.0
rrna maturation rnase ybeyHI_RS00020P71335-3854 - 431817356.4

Displaying genes 81 – 90 of 3606 in total

Pathways

25 pathways

Metabolites

188 records
Metabolite IDMetabolite nameStructureCAS number
BASm0018526CDP-DG(12:0/16:1(9Z))C40H71N3O15P2Chemical structure of CDP-DG(12:0/16:1(9Z))NULL
Average895.962Da
Monoisotopic895.436042594Da
BASm0018533CDP-DG(14:0/16:0)C42H77N3O15P2Chemical structure of CDP-DG(14:0/16:0)NULL
Average926.032Da
Monoisotopic925.482992787Da
BASm0018559CDP-DG(16:1(9Z)/18:1(9Z))C46H81N3O15P2Chemical structure of CDP-DG(16:1(9Z)/18:1(9Z))NULL
Average978.108Da
Monoisotopic977.514292916Da
BASm00188761-Acyl-sn-glycero-3-phosphoethanolamine (N-C12:0)C17H36NO7PNot availableNULL
Average397.449Da
Monoisotopic397.222939501Da
BASm00188771-Acyl-sn-glycero-3-phosphoethanolamine (N-C14:0)C19H40NO7PChemical structure of 1-Acyl-sn-glycero-3-phosphoethanolamine (N-C14:0)NULL
Average425.4972Da
Monoisotopic425.254239151Da
BASm00188791-Acyl-sn-glycero-3-phosphoethanolamine (N-C16:0)C21H44NO7PChemical structure of 1-Acyl-sn-glycero-3-phosphoethanolamine (N-C16:0)NULL
Average453.5503Da
Monoisotopic453.285539279Da
BASm00188811-Acyl-sn-glycero-3-phosphoethanolamine (N-C18:0)C23H48NO7PChemical structure of 1-Acyl-sn-glycero-3-phosphoethanolamine (N-C18:0)NULL
Average481.6035Da
Monoisotopic481.316839407Da
BASm00188831-Acyl-sn-glycero-3-phosphoglycerol (N-C12:0)C18H36O9PChemical structure of 1-Acyl-sn-glycero-3-phosphoglycerol (N-C12:0)NULL
Average427.4468Da
Monoisotopic427.209694262Da
BASm00188841-Acyl-sn-glycero-3-phosphoglycerol (N-C14:1)C20H38O9PChemical structure of 1-Acyl-sn-glycero-3-phosphoglycerol (N-C14:1)NULL
Average453.4841Da
Monoisotopic453.225344326Da
BASm00188851-Acyl-sn-glycero-3-phosphoglycerol (N-C16:0)C22H44O9PChemical structure of 1-Acyl-sn-glycero-3-phosphoglycerol (N-C16:0)NULL
Average483.5531Da
Monoisotopic483.272294518Da

Displaying 131–140 of 188 metabolites