Haemophilus influenzae Rd KW20

Gram-negativeRodNon-motileAerobe; facultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Pasteurellales

Family

Pasteurellaceae

Genus

Haemophilus

Description

Haemophilus influenzae Rd KW20 is a Gram-negative, rod-shaped bacterium that thrives optimally at a temperature of 35-37 °C. As a chemoheterotroph, it derives its energy from organic compounds, relying on the organic matter present in its environment for growth. This microbe is primarily found in the human respiratory tract, specifically in the nasopharynx and can also be isolated from various other body sites, including the ears, lungs, and sinuses. Classified as a facultative anaerobe, it can live in both aerobic and anaerobic conditions, making it adaptable to a range of environments within the host. H. influenzae Rd KW20 is notable for its role in human health; while it is part of the normal flora of the upper respiratory tract in healthy individuals, it can become pathogenic under certain circumstances. It is known to cause a range of infections, including pneumonia, sinusitis, and otitis media, particularly in children and immunocompromised adults.As a strain in the study of bacterial genetics, H. influenzae Rd KW20 has contributed to significant advancements in the understanding of molecular biology and genetics. Remarkably, it was one of the first organisms to have its genome completely sequenced, providing valuable insights into bacterial evolution, pathogenic mechanisms, and antibiotic resistance. Moreover, its relatively simple genetic makeup makes it an ideal model organism for laboratory studies, facilitating research in areas such as gene expression, protein function, and microbial interactions within the host.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderPasteurellales
FamilyPasteurellaceae
GenusHaemophilus
SpeciesHaemophilus influenzae
StrainRd KW20

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Haemophilus influenzae Rd KW20
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe; facultative anaerobe
Optimal temperature35
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityYes

Genome Summary

Haemophilus influenzae Rd KW20

Accession NumberNC_000907.1

Gene Summary

Adenine Count

567623 bp

Thymine Count

564241 bp

Guanine Count

347436 bp

Cytosine Count

350723 bp

Genome Length

1830138 bp

Protein-coding Genes

1663 genes

Non-Coding Genes

140 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
Transposase bHI_RS07655P96343+1564041 - 156490431489.8
Hypothetical proteinHI_RS07660P44210+1564965 - 156528211985.9
Host-nuclease inhibitor proteinHI_RS07665O05070+1565297 - 156580619194.0
hypothetical proteinHI_RS09005P44211+1565803 - 15659646359.29
hypothetical proteinHI_RS07670Not Available+1565964 - 156623310059.8
anr family transcriptional regulatorHI_RS07675P44212+1566436 - 15666578834.26
hypothetical proteinHI_RS09010P44213+1566657 - 15668306588.2
Hypothetical proteinHI_RS07680P44214+1566833 - 156739321638.0
Hypothetical proteinHI_RS07685P71387+1567567 - 156812420844.8
Hypothetical proteinHI_RS07690P44215+1568121 - 156867520783.2

Displaying genes 31 – 40 of 3606 in total

Pathways

25 pathways

Metabolites

188 records
Metabolite IDMetabolite nameStructureCAS number
BASm00188861-Acyl-sn-glycero-3-phosphoglycerol (N-C16:1)C22H42O9PChemical structure of 1-Acyl-sn-glycero-3-phosphoglycerol (N-C16:1)NULL
Average481.5372Da
Monoisotopic481.256644454Da
BASm00188881-hexadecanoyl-sn-glycerol 3-phosphateC19H39O7PChemical structure of 1-hexadecanoyl-sn-glycerol 3-phosphateNULL
Average410.4825Da
Monoisotopic410.243340114Da
BASm00188942-Acyl-sn-glycero-3-phosphoethanolamine (N-C12:0)C17H36NO7PNot availableNULL
Average397.449Da
Monoisotopic397.222939501Da
BASm00188952-Acyl-sn-glycero-3-phosphoethanolamine (N-C14:0)C19H40NO7PNot availableNULL
Average425.503Da
Monoisotopic425.25423963Da
BASm00188972-Acyl-sn-glycero-3-phosphoethanolamine (N-C16:0)C21H44NO7PChemical structure of 2-Acyl-sn-glycero-3-phosphoethanolamine (N-C16:0)NULL
Average453.5503Da
Monoisotopic453.285539279Da
BASm00188992-Acyl-sn-glycero-3-phosphoethanolamine (N-C18:0)C23H48NO7PChemical structure of 2-Acyl-sn-glycero-3-phosphoethanolamine (N-C18:0)NULL
Average481.6035Da
Monoisotopic481.316839407Da
BASm00189012-Acyl-sn-glycero-3-phosphoglycerol (N-C14:0)C20H40O9PChemical structure of 2-Acyl-sn-glycero-3-phosphoglycerol (N-C14:0)NULL
Average455.5Da
Monoisotopic455.24099439Da
BASm00189022-Acyl-sn-glycero-3-phosphoglycerol (N-C14:1)C20H38O9PChemical structure of 2-Acyl-sn-glycero-3-phosphoglycerol (N-C14:1)NULL
Average453.4841Da
Monoisotopic453.225344326Da
BASm00189032-Acyl-sn-glycero-3-phosphoglycerol (N-C16:0)C22H44O9PChemical structure of 2-Acyl-sn-glycero-3-phosphoglycerol (N-C16:0)NULL
Average483.5531Da
Monoisotopic483.272294518Da
BASm00189042-Acyl-sn-glycero-3-phosphoglycerol (N-C16:1)C22H42O9PChemical structure of 2-Acyl-sn-glycero-3-phosphoglycerol (N-C16:1)NULL
Average481.5372Da
Monoisotopic481.256644454Da

Displaying 141–150 of 188 metabolites